Wednesday, January 28, 2015

KIR and HLA genotypes have no identifiable role in single-unit dominance following double-unit umbilical cord blood transplantation

In this cohort of 83 double-unit CBT recipients, we failed to find an association between KIR and HLA genotypes with unit dominance. However, our small sample size and the limited number of CB pairs with unilateral NK alloreactivity may have precluded us in finding an association if one exists. The role of KIR and HLA genotypes in unit dominance still cannot be excluded and larger studies investigating this question are warranted (read more)