Donor Exposures in Recipients of Pooled Platelet Concentrates

The overall relative increase in donor exposures with the use of pooled platelet concentrates was similar in the two institutions (43% in Germany and 45% in Canada). The highest relative increase in donor exposures was 88% and 60%, respectively, and was observed in patients receiving fewer than 10 transfusions. Both percentages are far less than the currently anticipated 300% to 500% increase in donor exposures, which may be four to six times as high among patients who receive pooled platelet concentrates as among patients who receive apheresis platelet concentrates (read more)